NAD+ (Nicotinamide Adenine Dinucleotide) (500mg) Dosage Protocol
NAD+ is a coenzyme found in all living cells, essential for cellular energy production, DNA repair, and sirtuin activation. Injectable NAD+ bypasses digestive breakdown to directly support cellular NAD+ levels.
Add 3.0 mL bacteriostatic water → 166.7 mg/mL
50-250 mg per injection, frequency varies
At 166.7 mg/mL: 3 units = 50 mg, 15 units = 250 mg
Lyophilized: -20°C; Reconstituted: 2-8°C for up to 2 weeks
| Week | Daily Dose | Units (per injection) |
|---|---|---|
| Loading (optional) | 100-250 mg daily | 10-25 units for 5-7 days |
| Maintenance | 50-100 mg | 5-10 units 2-3x weekly |
| IV protocols | 250-500 mg | Slow IV infusion |
- 1Draw 3.0 mL bacteriostatic water with a sterile syringe
- 2Inject slowly into the vial
- 3Gently swirl until fully dissolved
- 4Label with date and concentration, refrigerate immediately
NAD+ is essential for mitochondrial function, serving as an electron carrier in the citric acid cycle and oxidative phosphorylation. It also activates sirtuins (SIRT1-7), which regulate metabolism, stress response, and longevity pathways. Levels decline with age.
- Supports cellular energy production
- Activates sirtuin longevity pathways
- May support DNA repair mechanisms
- Research suggests cognitive benefits
- Yoshino J, et al. NAD+ intermediates. Cell Metab. 2018
- Rajman L, et al. Therapeutic potential of NAD-boosting molecules. Cell Metab. 2018
- NAD+ and aging research studies
Lyophilized
Store at -20°C, protected from light
Reconstituted
Refrigerate at 2-8°C, use within 2 weeks
Sensitive to light and heat - handle carefully
- •Research compound for longevity studies
- •SubQ may cause flushing initially
- •IV infusion requires medical supervision
- •Combine with precursors (NMN, NR) for sustained levels
Disclaimer: This content is intended for research and educational purposes only. Not intended to diagnose, treat, cure, or prevent any disease. All compounds are for research use only. Dosing information is derived from published scientific literature and clinical studies.